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Clinical trials for Oxidative Stress

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   43881   clinical trials with a EudraCT protocol, of which   7295   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    214 result(s) found for: Oxidative Stress. Displaying page 1 of 11.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2006-005331-25 Sponsor Protocol Number: cru001-06 Start Date*: 2007-01-19
    Sponsor Name:Swansea NHS Trust
    Full Title: A study to examine the influence of repaglinide on the 'incretin effect' and oxidative damage associated with postprandial
    Medical condition: Type II Diabetes Mellitus
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-003262-17 Sponsor Protocol Number: AG-1-2007. Start Date*: 2008-08-13
    Sponsor Name:University Hospital Magdeburg
    Full Title: Impact of irbesartan on oxidative stress and C-reactive protein levels in patients with persistent atrial fibrillation
    Medical condition: Blocking the angiotensin II type 1 receptor reduces systemic levels of oxidative stress markers and adhesion molecules compared to placebo in patients with persistent/permanent atrial fibrillation.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2005-004171-37 Sponsor Protocol Number: CH/2005/1944 Start Date*: 2006-08-02
    Sponsor Name:United Bristol Healthcare Trust
    Full Title: Oxidative Stress in children undergoing cardiopulmonary bypass: A trial of Sildenafil therapy
    Medical condition: Congenital Heart Disease
    Disease:
    Population Age: Newborns, Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-000959-92 Sponsor Protocol Number: 2014-647 Start Date*: 2014-04-24
    Sponsor Name:Department of Clinical Pharmacology Q
    Full Title: A randomized, double-blinded, Placebo controlled study of simvastatins possible effect on oxidative stress on healthy volunteers
    Medical condition: Simvasatins effect on Oxidative Stress
    Disease: Version SOC Term Classification Code Term Level
    17.0 10022891 - Investigations 10022891 Investigations SOC
    Population Age: Adults Gender: Male
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-002214-13 Sponsor Protocol Number: IIBSP-OXI-2013-62 Start Date*: 2013-10-28
    Sponsor Name:Institut de Recerca de l?Hospital de la Santa Creu i Sant Pau ? IIB Sant Pau
    Full Title: Evaluation of oxidative stress associated with the administration of two different concentrations of oxygen for the maintenance of general anesthesia
    Medical condition: General anesthesia and oxidative stress
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-006837-28 Sponsor Protocol Number: PML_DOC_0804 Start Date*: 2008-12-08
    Sponsor Name:University Hospital Antwerp; Department Respiratory Medicine
    Full Title: Double blind, randomized, placebo-controlled, two-way crossover, pilot study to assess the effect of high dose N-acetylcysteine on small airways and on inflammation and oxidative stress in COPD pat...
    Medical condition: Chronic Obstructive Pulmonary Disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-003946-13 Sponsor Protocol Number: PML_NAC_01 Start Date*: 2007-09-05
    Sponsor Name:University Hospital Antwerp; Department Respiratory Medicine
    Full Title: Double blind, randomized, placebo-controlled, two-way crossover, pilot study to assess the effect of high dose N acetylcysteine on small airways and on inflammation and oxidative stress in COPD pat...
    Medical condition: Chronic Obstructive Pulmonary Disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-003651-12 Sponsor Protocol Number: NAC-E-23 Start Date*: 2005-11-11
    Sponsor Name:ZAMBON, S.A.
    Full Title: NAC EFFECT ON OXIDATIVE STRESS AND MUSCLE FUNCTION IN COPD PATIENTS. Efecto de NAC en estrés oxidativo y función muscular en pacientes con EPOC
    Medical condition: CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD).
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2004-001862-42 Sponsor Protocol Number: MeBN/02/Zof-AMI/001 Start Date*: 2005-02-17
    Sponsor Name:Clinical Research Facilities
    Full Title: A multicenter, double-blind, randomized 2x2 factorial design study to compare the efficacy of early (<6 hours) versus late (24-48 hours) ACE-inhibition and to compare the efficacy of Zofenopril an...
    Medical condition: Study population: Subjects undergoing a primary percutaneous coronary intervention (PCI) to be performed within 6 hours after the onset of symptoms of a first acute anterior myocardial infarction ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Completed)
    Trial results: View results
    EudraCT Number: 2011-005717-36 Sponsor Protocol Number: 1645-CI-057 Start Date*: 2012-06-14
    Sponsor Name:Instituto de Investigación Sanitaria La Fe
    Full Title: Extremely low gestational age neonates randomly an assigned to be blindly resuscitated with 21% vs. 60% oxygen: influence upon mortality and chronic conditions in the neonatal period.
    Medical condition: Preterm infants aged 30 weeks or less, who need resuscitation / stabilization maneuvers with positive pressure ventilation immediately after birth
    Disease:
    Population Age: Preterm newborn infants, Under 18 Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2016-002915-17 Sponsor Protocol Number: FIM-EOX-2016-01 Start Date*: 2016-11-03
    Sponsor Name:Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud (FIMABIS)
    Full Title: Impact on oxidative stress of novel analogues of insulin in people with type 1 diabetes. Low- intervention clinical trial. Ineox Study
    Medical condition: DIABETES TYPE 1
    Disease: Version SOC Term Classification Code Term Level
    19.0 10027433 - Metabolism and nutrition disorders 10022491 Insulin resistant diabetes PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-006736-22 Sponsor Protocol Number: NAF 03.4.05.033 Start Date*: 2007-02-14
    Sponsor Name:Netherlands Asthma Foundation (NAF) [...]
    1. Netherlands Asthma Foundation (NAF)
    2. Stichting astma bestrijding
    Full Title: An early diagnosis of asthma in young children by using non-invasive biomarkers of oxidative stress/airway inflammation, and early lung function measurements
    Medical condition: children with recurrent respiratory symptoms)
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: NL (Not Authorised)
    Trial results: (No results available)
    EudraCT Number: 2012-000152-34 Sponsor Protocol Number: 2012-000152-34 Start Date*: 2012-02-09
    Sponsor Name:AZIENDA UNIVERSITARIA POLICLINICO UMBERTO I DI ROMA
    Full Title: evaluation of the effect of treatment with DPP-4 inhibitor on endothelial function versus sulphonylurea on markers of oxidative stress and inflammation and platelet function in patients with diabet...
    Medical condition: Type 2 diabetes
    Disease: Version SOC Term Classification Code Term Level
    14.1 10027433 - Metabolism and nutrition disorders 10027433 Metabolism and nutrition disorders SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-004995-17 Sponsor Protocol Number: NL7507301820 Start Date*: 2021-03-11
    Sponsor Name:AMsterdam UMC-AMC
    Full Title: Low dose iron chelation as TReatment of Oxidative stress in Sickle cell disease; TROS study
    Medical condition: Sickle cell disease (an hereditary hemoglobinopathy)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-001948-60 Sponsor Protocol Number: DOSFEM Start Date*: 2013-09-09
    Sponsor Name:Sint Franciscus Gasthuis Rotterdam
    Full Title: Effects of high and low dose vitamin D on postprandial leukocyte activation, oxidative stress and vascular function in healthy overweight and obese females
    Medical condition: 'healthy volunteers' 'atherosclerosis' 'vitamin D deficiency'
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-003088-76 Sponsor Protocol Number: 11-170 Start Date*: 2014-07-14
    Sponsor Name:Clinical Evaluation Research Unit (CERU)
    Full Title: SodiUm SeleniTe Adminstration IN Cardiac Surgery surgery (SUSTAIN CSX®-trial) - A randomized controlled trial of high dose sodium-selenite administration in high risk cardiac surgical patients
    Medical condition: Selenium is a key component of a number of selenoproteins which protect against oxidative stress and is well recognised for its prominent role in immune defence. Selenoproteins have the potential t...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-004406-18 Sponsor Protocol Number: INRCA-2017-01 Start Date*: 2019-02-14
    Sponsor Name:IRCC INRCA
    Full Title: Geriatric outcomes among older Type 2 diabetic patients treated with DPP4 inhibitors or glinides: focus on pro-inflammatory and oxidative stress markers (GOOD-WP1)
    Medical condition: TYPE 2 DIABETES
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004861 10045242 Type II diabetes mellitus LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2016-001417-24 Sponsor Protocol Number: PLEIADES Start Date*: 2017-02-22
    Sponsor Name:Franciscus Gasthuis
    Full Title: POSTPRANDIAL LIPEMIA, INFLAMMATION, AND VASCULAR FUNCTION IN DIABETES MODULATED BY SGLT2 INHIBITION
    Medical condition: Diabetes Mellitus type II
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-001817-40 Sponsor Protocol Number: NAF 3.4.05.003 Start Date*: 2007-05-10
    Sponsor Name:Netherlands Asthma Foundation (NAF) [...]
    1. Netherlands Asthma Foundation (NAF)
    2. Stichting astma bestrijding
    Full Title: An early diagnosis of asthma in young children by using non-invasive biomarkers of oxidative stress/airway inflammation
    Medical condition: young children with recurrent respiratory symptoms
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-020698-17 Sponsor Protocol Number: 2010_3 Start Date*: 2010-10-04
    Sponsor Name:Antwerp University Hospital : Department Respiratory Medicine
    Full Title: Study of the vascular wall with functional imaging in OSA patients.
    Medical condition: Obstructive sleep apnea (OSA) is a prevalent disorder and characterised by sleepiness during the daytime, fatigue and impairments of concentration. OSA can also lead to cardiovascular pathology due...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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